>> A complete list of publications is available on Pubmed (link) and Google Scholar (link). <<
2026
209. Kaminer A, Li Y, Barth HD, Dietz MS, Heilemann M, Quantitative Mapping of Nanoscale EGFR–Grb2 Assemblies by DNA-PAINT, Chemistry Europe Open Access 22. April 2026, 10.1002/cphc.202500915
208. Kaltenschnee N, Dietz MS, Kessler LF, Li Y, Kaufmann J, Heckel A, Heilemann M, Wash-Free Multi-Target Super-Resolution Microscopy With Photocaged DNA Labels, Angew Chem Int Ed Engl. 2026 Mar 13:e26137. anie.202526137.
207. Kessler LF, Li Y, Balakrishnan A, Heilemann M, Quantitative Stimulated Emission Depletion (STED) Microscopy with DNA-Fluorophore Labels, ACS Nano. 2026 Feb 17;20(6):5288-5296. acsnano.5c21411. Epub 2026 Feb 3.
206. Kompa J, Dornfeld LJ, Porzberg N, Jang S, Zedlitz S, Lilje SH, Catapano C, Jocher D, Merk L, Hoege C, Mao R, Wilhelm J, Dietz MS, Tarnawski M, Hiblot J, Hyman AA, Heilemann M, Johnsson K, Fast, Bright, and Reversible Fluorescent Labeling of Rhodamine-Binding Proteins, J Am Chem Soc. 2026 Jan 14;148(1):1419-1429. jacs.5c18083. Epub 2025 Dec 30.
205. Li Y, Dietz MS, Barth HD, Niemann HH, Heilemann M, Single-Molecule FRET-Tracking of InlB-Activated MET Receptors in Living Cells, Small. 2026 Jan;22(5):e07115. smll.202507115. Epub 2025 Dec 19.
204. Hacke M, Kaplan Ch, Laketa v, Heilemann M, Müller B, Kräusslich HG, Multiplex 3D Nanoscopy Resolves Nanoarchitecture of Human Immunodeficiency Virus, ACS Nano. 2026 Jan 20;20(2):1911-1927. acsnano.5c12222. Epub 2025 Dec 14.
203. Schroeter HG, Sass S, Heilemann M, Kuner T, Klevanski M, Nanoscale Mapping of the Subcellular Glycosylation Landscape, Wiley Advanced, Adv Sci (Weinh). 2026 Feb;13(11):e06731. advs.202506731. Epub 2025 Nov 10.
2025
202. Berrevoets ES, Kessler LF, Balakrishnan A, Okuda EK, Müller-McNicoll M, Rieder B, Stallinga S, Heilemann M, Smart 3D super-resolution microscopy reveals the architecture of the RNA scaffold in a nuclear body, Nature communications, 27 Nov 2025: 10689
201. Saguy A, Xiao D, Narayanasamy KK, Nakatani Y, Saliba N, Gagliano G, Gustavsson AK, Heilemann M, Shechtman Y, One-click reconstruction in single-molecule localization microscopy via experimental parameter-aware deep learnin, Npj Imaging. 2025 Nov 25;3(1):61.
200. Kazumi Okuda E, Kessler LF, Arnold B, Riegger J R, Hernández Cañás MC, Zebrowska E, Bakisoglu C, Rudigier M, Krost Ch, Nagasse Y H, Keiten-Schmitz J, Müller St, Stanek D, Dormann D, Zarnack K, Heilemann M, Müller-McNicoll M, Rapid depletion and super-resolution microscopy reveal dual roles of SRSF5 in coordinating nuclear speckle–paraspeckle crosstalk during cellular stress, Nucleic Acids Research, Volume 53, Issue 14, 12 August 2025, gkaf713
199. Saguy A, Xiao D, Narayanasamy KK, Nakatani Y, Gustavsson AK, Heilemann M, Shechtman Y, One-click image reconstruction in single-molecule localization microscopy via deep learning, Nat. Communi. 25.11.2025:61
198. Kazumi Okuda E, Kessler, LF, A new rapid-degradation system combined with super-resolution microscopy. Nat Rev Mol Cell Biol (2025).
197. Spahn C, Middlemiss S, Gómez-de-Mariscal E, Henriques R, Bode HB, Holden S, Heilemann M, The nucleoid of rapidly growing Escherichia coli localizes close to the inner membrane and is organized by transcription, translation, and cell geometry, Nat Commun.
2025 Apr 20, 16(1):3732
196. Grumati P, Morozzi G, Hölper S, Mari M, Harwardt MIE, Yan R, Müller S, Reggiori F, Heilemann M, Dikic I, Correction: Full length RTN3 regulates turnover of tubular endoplasmic reticulum via selective autophagy., Elife. 2025 Apr 15;14:e107151.
195. Rahm JV, Balakrishnan A, Wehrheim M, Kaminer A, Glogger M, Kessler LF, Kaschube M, Barth HD, Heilemann M, Fast and Long-Term Super-Resolution Imaging of Endoplasmic Reticulum Nano-structural Dynamics in Living Cells Using a Neural Network, Small Sci. 2024 Nov 8;5(1):2400385. smsc.202400385. eCollection 2025 Jan.
194. Catapano C, Dietz MS, Kompa J, Jang S, Freund P, Johnsson K, Heilemann M, Long-Term Single-Molecule Tracking in Living Cells Using Weak-Affinity Protein Labeling, Angew Chem Int Ed Engl. 2025 Jan 2;64(1):e202413117. anie.202413117. Epub 2024 Nov 25
193. Saguy A, Nahimov T, Lehrman M, Gómez-de-Mariscal E, Hidalgo-Cenalmor I, Alalouf O, Balakrishnan A, Heilemann M, Henriques R, Shechtman Y, This Microtubule Does Not Exist: Super-Resolution Microscopy Image Generation by a Diffusion Model, Small Methods (2024 Oct 14), e2400672.
2024
192. Li Y, Arghittu SM, Dietz MS, Hella GH, Haße D, Ferraris DM, Freund P, Barth HD, Iamele L, Jonge Hd, Niemann HH, Covino R, Heilemann M, Single-molecule imaging and molecular dynamics simulations reveal early activation of the MET receptor in cells, Nat Commun ( 2024 Nov 2), 15(1):9486.
191. Birtasu AN, Ermel UH, Rahm JV, Seybert A, Flottmann B, Heilemann M, Grahammer F, Frangakis AS, Localization of albumin with correlative super resolution light- and electron microscopy in the kidney, J Struct Biol X (Oct. 2024), 100114
190. Osuna-Varga P, Wehrheim MH, Zinz L, Rahm J, Balakrishnan A, Kaminer A, Heilemann M, Kaschube M, Denoising diffusion models for high-resolution microscopy image restoration, arXiv:2409.12078 [eess.IV] (2024 Sep 18)
189. Balakrishnan A, Glogger M, Heilemann M, Quantitative Super-Resolution Imaging of ER-Phagy Initiation in Cells, Methods Mol Biol. (2024), 2845:127-140.
188. Mineev KS, Hargittay B, Jin J, Catapano C, Dietz MS, Segarra M, Harwardt MS, Richter C, Jonker HRA, Saxena K, Sreeramulu S, Heilemann M, Acker-Palmer A, Schwalbe H, Differential effects of the N-terminal helix of FGF8b on the activity of a small-molecule FGFR inhibitor in cell culture and for the extracellular domain of FGFR3c in solution, FEBS Lett., (2024 July 12)
187. Kessler LF, Balakrishnan A, Menche T, Wang D, Li Y, Mantel M, Glogger M, Dietz MS, Heilemann M, Self-Quenched Fluorophore-DNA Labels for Super-Resolution Fluorescence Microscopy, J. Phys. Chem. B (2024 July 02), 128(28):6751-6759
186. Klevanski M, Kim H, Heilemann M, Thomas Kuner Th, Ralf Bartenschlager, Glycan-directed SARS-CoV-2 inhibition by leek extract and lectins with insights into the mode-of-action of Concanavalin A, Antiviral Research (May 2024), 225:105856.
185. Abraham BG, Haikarainen T, Vuorio J, Girych M, Virtanen AT, Kurttila A, Karathanasis C, Heilemann M, Sharma V, Vattulainen I, Silvennoinen O, Molecular basis of JAK2 activation in erythropoietin receptor and pathogenic JAK2 signaling, Sci Adv. (2024 Mar 08, 10(10):eadl2097
184. Bestsennaia E, Maslov I, Balandin T, Alekseev A, Yudenko A, Abu Shamseye A, Zabelskii D, Baumann A, Catapano C, Karathanasis C, Gordeliy V, Heilemann M, Gensch T, Borshchevskiy V, Revealing the Oligomerization of Channelrhodopsin-2 in the Cell Membrane using Photo-Activated Localization Microscopy, Angew Chem Int Ed Engl. (2024 Mar 11), 63(11):e202307555
2023
183. Berkane R, Ho-Xuan H, Glogger M, Sanz-Martinez P, Brunello L, Glaesner T, Kuncha SK, Holzhüter K, Cano-Franco S, Buonomo V, Cabrerizo-Poveda P, Balakrishnan A, Tascher G, Husnjak K, Juretschke T, Misra M, González A, Dötsch V, Grumati P, Heilemann M, Stolz A, The function of ER-phagy receptors is regulated through phosphorylation-dependent ubiquitination pathways, Nat Commun. (2023 Dec 15), 14(1):8364.
182. Jang S, Narayanasamy KK, Rahm JV, Saguy A, Kompa J, Dietz MS, Johnsson K, Shechtman Y, Heilemann M, Neural network-assisted single-molecule localization microscopy with a weak-affinity protein tag, Biophys Rep (N Y), (2023 Aug 18), 3(3):100123.
181. Kessler LF, Balakrishnan A, Deußner-Helfmann NS, Li Y, Mantel M, Glogger M, Barth HD, Dietz MS, Heilemann M, Self-quenched Fluorophore Dimers for DNA-PAINT and STED Microscopy, Angew Chem Int Ed Engl. (2023 Sep 25), 62(39):e202307538.
180. Saguy A, Alalouf O, Opatovski N, Jang S, Heilemann M, Shechtman Y, DBlink: dynamic localization microscopy in super spatiotemporal resolution via deep learning, Nat Methods. (2023 Dec 20), (12):1939-1948.
179. González A, Covarrubias-Pinto A, Bhaskara RM, Glogger M, Kuncha SK, Xavier A, Seemann E, Misra M, Hoffmann ME, Bräuning B, Balakrishnan A, Qualmann B, Dötsch V, Schulman BA, Kessels MM, Hübner CA, Heilemann M, Hummer G, Dikić I, Ubiquitination regulates ER-phagy and remodelling of endoplasmic reticulum, (Nature. 2023 Jun), 618(7964):394-401.
178. Catapano C, Rahm JV, Omer M, Teodori L, Kjems J, Dietz MS, Heilemann M, Biased activation of the receptor tyrosine kinase HER2, Cell Mol Life Sci. (2023 May 20), 80(6):158.
177. Albertazzi L, Heilemann M, When Weak Is Strong: A Plea for Low-Affinity Binders for Optical Microscopy, Angew Chem Int Ed Engl. (2023 Aug 28), 62(35):e202303390.
176. Nieves DJ, Pike JA, Levet F, Williamson DJ, Baragilly M, Oloketuyi S, de Marco A, Griffié J, Sage D, Cohen EAK, Sibarita JB, Heilemann M, Owen DM, A framework for evaluating the performance of SMLM cluster analysis algorithms, Nat Methods. (2023 Feb.), 20(2):259-267.
175. Kompa J, Bruins J, Glogger M, Wilhelm J, Frei MS, Tarnawski M, D'Este E, Heilemann M, Hiblot J, Johnsson K, Exchangeable HaloTag Ligands for Super-Resolution Fluorescence Microscopy, J Am Chem Soc. (2023 Feb 08), 145(5):3075-3083.
2022
174. Verzelli P, Nold A, Sun C, Heilemann M, Schuman EM, Tchumatchenko T, Unbiased choice of global clustering parameters for single-molecule localization microscopy, Sci Rep. (2022 Dec 29), 12(1):22561.
173. Sánchez MF, Dietz MS, Müller U, Weghuber J, Gatterdam K, Wieneke R, Heilemann M, Lanzerstorfer P, Tampé R, Dynamic in Situ Confinement Triggers Ligand-Free Neuropeptide Receptor Signaling, Nano Lett. (2022 Oct 26), 22(20):8363-8371.
172. Glogger M, Wang D, Kompa J, Balakrishnan A, Hiblot J, Barth HD, Johnsson K, Heilemann M, Synergizing Exchangeable Fluorophore Labels for Multitarget STED Microscopy, ACS Nano. (2022 Nov 22), 16(11):17991-17997.
171. Koller N, Höllthaler P, Barends M, Döring M, Spahn C, Durán V, Costa B, Becker J, Heilemann M, Kalinke U, Tampé R, Nanoscale organization of the MHC I peptide-loading complex in human dendritic cells, Cell Mol Life Sci. (2022 Aug 10), 79(9):477.
170. Narayanasamy KK, Rahm JV, Tourani S, Heilemann M, Fast DNA-PAINT imaging using a deep neural network, Nat Commun. (2022 Aug 27), 13(1):5047.
169. Karathanasis C, Sanchez CP, Heilemann M, Lanzer M, Assessing Antigen Presentation on the Surface of Plasmodium falciparum-Infected Erythrocytes by Photoactivated Localization Microscopy (PALM), In: Jensen, A.T.R., Hviid, L. (eds) Malaria Immunology., Humana, New York, NY, Methods Mol Biol. (2022), 2470:457-466.
168. Spahn C, Gómez-de-Mariscal E, Laine RF, Pereira PM, von Chamier L, Conduit M, Pinho MG, Jacquemet G, Holden S, Heilemann M, Henriques R, DeepBacs for multi-task bacterial image analysis using open-source deep learning approaches, Commun Biol. (2022 Jul 09), 5(1):688.
167. Yadav S, Centola M, Glaesmann M, Pogoryelov D, Ladig R, Heilemann M, Rai LC, Yildiz Ö, Schleiff E, Cyclophilin anaCyp40 regulates photosystem assembly and phycobilisome association in a cyanobacterium, Nat Commun. (2022 Mar 30), 13(1):1690.
166. Rahm JV, Malkusch S, Endesfelder U, Dietz MS, Heilemann M, Extraction of diffusion state transitions in single-particle tracking data of membrane receptors, Single Molecule Spectroscopy and Superresolution Imaging XV 11967 (2022), 11967, 22-30
165. Malkusch S, Rahm JV, Dietz MS, Heilemann M, Sibarita JB, Lötsch J, Receptor tyrosine kinase MET ligand-interaction classified via machine learning from single-particle tracking data, Mol Biol Cell. (2022 May 15), 33(6):ar60.
164. Sanchez CP, Patra P, Chang SS, Karathanasis C, Hanebutte L, Kilian N, Cyrklaff M, Heilemann M, Schwarz US, Kudryashev M, Lanzer M, Mol Microbiol. (2022 Feb), 117(2):274-292.
2021
163. Rahm JV, Malkusch S, Endesfelder U, Dietz MS & Heilemann M (2021) Diffusion state transitions in single-particle trajectories of MET receptor tyrosine kinase measured in live cells. Front Comput Sci 3, 104 (2021), 3, 757653
162. Sun C, Nold A, Fusco CM, Rangaraju V, Tchumatchenko T, Heilemann M, Schuman EM, The prevalence and specificity of local protein synthesis during neuronal synaptic plasticity, Sci Adv. (2021 Sep 17), 7(38):eabj0790.
161. de Jesus V, Qureshi NS, Warhaut S, Bains JK, Dietz MS, Heilemann M, Schwalbe H, Fürtig B, Switching at the ribosome: riboswitches need rProteins as modulators to regulate translation. Nat Commun. (2021 Aug 05), 12(1):4723.
160. Liu Y, Mukherjee R, Bonn F, Colby T, Matic I, Glogger M, Heilemann M, Dikic I, Serine-ubiquitination regulates Golgi morphology and the secretory pathway upon Legionella infection. Cell Death Differ. (2021 Oct), 28(10):2957-2969.
159. Narayanasamy KK, Stojic A, Li Y, Sass S, Hesse MR, Deussner-Helfmann NS, Dietz MS, Kuner T, Klevanski M, Heilemann M, Visualizing multi-protein patterns at the synapse of neuronal tissue with DNA-assisted single-molecule localization microscopy. Front Synaptic Neurosci. (2021 Jun 17), 13:671288.
158. Malkomes P, Lunger I, Oppermann E, Abou-El-Ardat K, Oellerich T, Günther S, Canbulat C, Bothur S, Schnütgen F, Yu W, Wingert S, Haetscher N, Catapano C, Dietz MS, Heilemann M, Kvasnicka HM, Holzer K, Serve H, Bechstein WO, Rieger MA, Transglutaminase 2 promotes tumorigenicity of colon cancer cells by inactivation of the tumor suppressor p53, Oncogene (2021 Jun), 40(25):4352-4367.
157. Saguy A, Baldering TN, Weiss LE, Nehme E, Karathanasis C, Dietz MS, Heilemann M, Shechtman Y, Automated analysis of fluorescence kinetics in single-molecule localization microscopy data reveals protein stoichiometry, J Phys Chem B (2021 Jun 10), 125(22):5716-5721.
156. von Chamier L, Laine RF, Jukkala J, Spahn C, Krentzel D, Nehme E, Lerche M, Hernández-Pérez S, Mattila PK, Karinou E, Holden S, Solak AC, Krull A, Buchholz TO, Jones ML, Royer LA, Leterrier C, Shechtman Y, Jug F, Heilemann M, Jacquemet G, Henriques R, Democratising deep learning for microscopy with ZeroCostDL4Mic, Nat Commun (2021 Apr 15), 12(1):2276.
155. Vo TD, Spahn C, Heilemann M, Bode HB, Microbial Cationic Peptides as a Natural Defense Mechanism against Insect Antimicrobial Peptides, ACS Chem Biol (2021 Mar 19), 16(3):447-451.
154. Glogger M, Spahn C, Enderlein J, Heilemann M, Multi-Color, Bleaching-Resistant Super-Resolution Optical Fluctuation Imaging with Oligonucleotide-based Exchangeable Fluorophores, Angew Chem Int Ed Engl (2021 Mar 15), 60(12):6310-6313.
153. Baldering TN, Karathanasis C, Harwardt MIE, Freund P, Meurer M, Rahm JV, Knop M, Dietz MS, Heilemann M, CRISPR/Cas12a-mediated labeling of MET receptor enables quantitative single-molecule imaging of endogenous protein organization and dynamics, iScience. (2020 Dec 07), 24(1):101895.
152. Schröder MS, Harwardt MIE, Rahm JV, Li Y, Freund P, Dietz MS, Heilemann M, Imaging the fibroblast growth factor receptor network on the plasma membrane with DNA-assisted single-molecule super-resolution microscopy, Methods (2021 Sep), 193, 38-45.
2020
151. Maillard J, Klehs K, Rumble C, Vauthey E, Heilemann M, Fürstenberg A, Universal quenching of common fluorescent probes by water and alcohols, (Chem Sci. 2020 Nov 19), 12(4):1352-1362.
150. Dutta S , Rühle J , Schikora M , Deussner-Helfmann N , Heilemann M , Zatsepin T , Duchstein P , Zahn D , Knör G , Mokhir A, Red light-triggered photoreduction on a nucleic acid template, Chem Commun (Camb) (2020 Sep 07), 56(69):10026-10029.
149. Möller J, Isbilir A, Sungkaworn T, Osberg B, Karathanasis C, Sunkara V, Grushevskyi EO, Bock A, Annibale P, Heilemann M, Schütte C, Lohse MJ, Single-molecule analysis reveals agonist-specific dimer formation of µ-opioid receptors, Nat Chem Biol (2020 Sep), 16(9):946-954.
148. Kumar R, Pereira RS, Zanetti C, Minciacchi VR, Merten M, Meister M, Niemann J, Dietz MS, Rüssel N, Schnütgen F, Tamai M, Akahane K, Inukai T, Oellerich T, Kvasnicka HM, Pfeifer H, Nicolini FE, Heilemann M, Van Etten RA, Krause DS, Specific, targetable interactions with the microenvironment influence imatinib-resistant chronic myeloid leukemia, Leukemia (2020 Aug), 34(8):2087-2101.
147. Weinelt N, Karathanasis C, Smith S, Medler J, Malkusch S, Fulda S, Wajant H, Heilemann M, van Wijk SJL, Quantitative single-molecule imaging of TNFR1 reveals zafirlukast as antagonist of TNFR1 clustering and TNFα-induced NF-kB signaling, J Leukoc Biol (2021 Feb), 109(2):363-371.
146. Harwardt MIE, Schröder MS, Li Y, Malkusch S, Freund P, Gupta S, Janjic N, Strauss S, Jungmann R, Dietz MS, Heilemann M, Single-Molecule Super-Resolution Microscopy Reveals Heteromeric Complexes of MET and EGFR upon Ligand Activation, Int J Mol Sci (2020 Apr 17), 21(8):2803.
145. Klevanski M, Herrmannsdoerfer F, Sass S, Venkataramani V, Heilemann M, Kuner T, Automated highly multiplexed super-resolution imaging of protein nano-architecture in cells and tissues, Nat Commun (2020 Mar 25), 11(1):1552.
144. Karathanasis C, Medler J, Fricke F, Smith S, Malkusch S, Widera D, Fulda S, Wajant H, van Wijk SJL, Dikic I, Heilemann M, Single-molecule imaging reveals the oligomeric state of functional TNFα-induced plasma membrane TNFR1 clusters in cells, Sci Signal (2020 Jan 14), 13(614):eaax5647.
2019
143. Spahn C, Hurter F, Glaesmann M, Karathanasis C, Lampe M, Heilemann M, Protein‐specific, multi‐color and 3D STED imaging in cells with DNA‐labeled antibodies, Angew Chem Int Ed Engl (2019 Dec 19), 58(52):18835-18838.
142. Dietz MS, Wehrheim SS, Harwardt MIE, Niemann HH, Heilemann M, Competitive binding study revealing the influence of fluorophore labels on biomolecular interactions, Nano Lett (2019 Nov 13), 19(11):8245-8249.
141. Dietz MS , Heilemann M, Optical super-resolution microscopy unravels the molecular composition of functional protein complexes, Nanoscale (2019 Oct 10), 11(39):17981-17991.
140. Baldering TN, Bullerjahn JT, Hummer G, Heilemann M, Malkusch S, Molecule counts in complex oligomers with single-molecule localization microscopy. J Phys D (2019), Appl Phys 52 (47), 474002.
139. Böger C, Hafner AS, Schlichthärle T, Strauss MT, Malkusch S, Endesfelder U, Jungmann R, Schuman EM, Heilemann M, Super-resolution imaging and estimation of protein copy numbers at single synapses with DNA-PAINT, Neurophotonics (2019 Jul), 6(3):035008.
138. Zozulia O, Bachmann T, Deussner-Helfmann NS, Beierlein F, Heilemann M, Mokhir A, Red Light Triggered Fluorogenic Reaction Sensitive to Few Copies of Nucleic Acids, Chem Commun (Camb) (2019 Sep 16), 55(72):10713-10716.
137. Sanchez CP, Karathanasis C, Sanchez R, Cyrklaff M, Jäger J, Buchholz B, Schwarz US, Heilemann M, Lanzer M, Single-molecule imaging and quantification of PfEMP1 adhesins on knobs of Plasmodium falciparum-infected erythrocytes, Commun Biol (2019 May 08), 2:172.
136. Böger C, Baldering TN, Krüger CL, Harwardt ML, Mertinkus KR, Schröder MS, Karathanasis C, Deussner-Helfmann NS, Barth HD, Malkusch S, Dietz MS, Hummer G, Wohland T, Heilemann M, Quantification of membrane receptor complexes with single-molecule localization microscopy, SPIE 10884 (2019), 10884, 62-70
135. Baldering TN, Dietz MS, Gatterdam K, Karathanasis C, Wieneke R, Tampé R, Heilemann M, Synthetic and genetic dimers as quantification ruler for single-molecule counting with PALM, Mol Biol Cell (2019 Jun 1), 30(12):1369-1376.
134. Spahn C, Grimm JB, Lavis LD, Lampe M, Heilemann M, Whole-Cell, 3D, and Multicolor STED Imaging with Exchangeable Fluorophores, Nano Lett (2019 Jan 09), 19(1):500-505.
133. van Wijk SJ, Fulda S, Dikic I, Heilemann M, Visualizing ubiquitination in mammalian cells, EMBO Rep (2019 Feb), 20(2):e46520.
2018
132. Spahn CK, Glaesmann M, Grimm JB, Ayala AX, Lavis LD, Heilemann M, A toolbox for multiplexed super-resolution imaging of the E. coli nucleoid and membrane using novel PAINT labels, Sci Rep. (2018 Oct 3), 8(1):14768.
131. Deußner-Helfmann NS, Auer A, Strauss MT, Malkusch S, Dietz MS, Barth HD, Jungmann R, Heilemann M, Correlative Single-Molecule FRET and DNA-PAINT Imaging, Nano Lett (2018 Jul 11), 18(7):4626-4630.
130. Klein A, Hank S, Raulf A, Joest EF, Tissen F, Heilemann M, Wieneke R, Tampé R, Live-cell labeling of endogenous proteins with nanometer precision by transduced nanobodies, Chem Sci (2018 Aug 20), 9, 40, 7835-7842.
129. Gao Y, Spahn C, Heilemann M, Kenney LJ, The Pearling Transition Provides Evidence of Force-Driven Endosomal Tubulation during Salmonella Infection, mBio (2018 Jun 19), 9(3):e01083-18.
128. Oppelt A, Kaschek D, Huppelschoten S, Sison-Young R, Zhang F, Buck-Wiese M, Herrmann F, Malkusch S, Krüger CL, Meub M, Merkt B, Zimmermann L, Schofield A, Jones RP, Malik H, Schilling M, Heilemann M, van de Water B, Goldring CE, Park BK, Timmer J, Klingmüller U, Model-based identification of TNFα-induced IKKβ- and IκBα-mediated regulation of NFκB signal transduction as a tool to quantify the impact of drug-induced liver injury compounds, NPJ Syst Biol Appl (2018 Jun 11), 4:23.
127. Harwardt ML, Dietz MS, Heilemann M, Wohland T, SPT and Imaging FCS Provide Complementary Information on the Dynamics of Plasma Membrane Molecules, Biophys J (2018 May 22), 114(10):2432-2443.
126. Venkataramani V, Kardorff M, Herrmannsdörfer F, Wieneke R, Klein A, Tampé R, Heilemann M, Kuner T, Enhanced labeling density and whole-cell 3D dSTORM imaging by repetitive labeling of target proteins, Sci Rep (2018 Apr 03), 8(1):5507.
125. Gatterdam K, Joest EF, Dietz MS, Heilemann M, Tampé R, Super-chelators for advanced protein labeling in living cells, Angew Chem Int Ed Engl (2018 May 14), 57(20):5620-5625.
124. Poppelreuther M, Sander S, Minden F, Dietz MS, Exner T, Du C, Zhang I, Ehehalt F, Knüppel L, Domschke S, Badenhop A, Staudacher S, Ehehalt R, Stremmel W, Thiele C, Heilemann M, Füllekrug J, The metabolic capacity of lipid droplet localized acyl-CoA synthetase 3 is not sufficient to support local triglyceride synthesis independent of the endoplasmic reticulum in A431 cells, Biochim Biophys Acta Mol Cell Biol Lipids (2018 Jun), 1863(6):614-624.
123. Vlijm R, Li X, Panic M, Rüthnick D, Hata S, Herrmannsdörfer F, Kuner T, Heilemann M, Engelhardt J, Hell SW, Schiebel E, STED nanoscopy of the centrosome linker reveals a CEP68-organised, periodic rootletin network anchored to a C-Nap1 ring at centrioles, Proc Natl Acad Sci U S A. (2018 Mar 6), 115(10):E2246-E2253.
2017
122. Krüger C, Zeuner M, Cottrell G, Widera D, Heilemann M, Quantitative single-molecule imaging of TLR4 reveals ligand-specific receptor dimerization. Sci Signal. (2017 Oct 31), 10(503):eaan1308.
121. Spahn C, Glaesmann M, Gao Y, Foo YH, Lampe M, Kenney LJ, Heilemann M, Sequential super-resolution imaging of bacterial regulatory proteins, the nucleoid and the cell membrane in single, fixed E. coli cells. Methods Mol Biol. (2017), 1624:269-289.
120. Stark T, Lieblein T, Pohland M, Kalden E, Freund P, Zangl R, Grewal R, Heilemann M, Eckert GP, Morgner N, Göbel MW, Peptidomimetics that inhibit and partially reverse the aggregation of Aβ1-42. Biochemistry. (2017 Sep 12), 56(36):4840-4849.
119. Harwardt ML, Young P, Bleymüller WM, Meyer T, Karathanasis C, Niemann HH, Heilemann M, Dietz MS, Membrane dynamics of resting and InlB-bound MET receptor tyrosine kinase studied by single-molecule tracking. FEBS Open Bio. (2017 Aug 29), 7(9):1422-1440.
118. Klötzner DP, Klehs K, Heilemann M, Heckel A, A new photoactivatable near-infrared-emitting QCy7 fluorophore for single-molecule super-resolution microscopy. Chem Commun (Camb). (2017 Aug 31), 53(71):9874-9877.
117. Polajnar M, Dietz MS, Heilemann M, Behrends C, Expanding the host cell ubiquitylation machinery targeting cytosolic Salmonella, EMBO Rep. (2017 Sep) 18(9):1572-1585.
116. Grumati P, Morozzi G, Hölper S, Mari M, Harwardt ML, Yan R, Müller S, Reggiori F, Heilemann M, Dikic I, Full length RTN3 regulates turnover of tubular endoplasmic reticulum via selective autophagy, Elife. (2017 Jun 15), 6:e25555.
115. van Wijk S, Fricke F, Herhaus L, Gupta J, Hötte K, Pampaloni F, Grumati P, Kaulich M, Sou Y, Komatsu M, Greten F, Simone F, Heilemann M, Dikic I, Linear ubiquitination of cytosolic Salmonella Typhimurium activates NF-κB and restricts bacterial proliferation, Nat Microbiol. (2017 May 8), 2:17066.
114. Sauer M, Heilemann M, Single-Molecule Localization Microscopy in Eukaryotes, Chem Rev. (2017 Jun 14), 117(11):7478-7509.
113. Karathanasis C, Fricke F, Hummer G, Heilemann M, Molecule counts in localization microscopy with organic fluorophores, Chemphyschem. (2017 Apr 19), 18(8):942-948.
112. Warhaut S, Mertinkus KR, Höllthaler P, Fürtig B, Heilemann M, Hengesbach M, Schwalbe H, Ligand-modulated folding of the full-length adenine riboswitch probed by NMR and single-molecule FRET spectroscopy. Nucleic Acids Res. (2017 May 19), 45(9):5512-5522.
111. Krüger C, Fricke F, Karathanasis C, Dietz MS, Malkusch S, Hummer G, Heilemann M, Molecular counting of membrane receptor subunits with single-molecule localization microscopy. Proc SPIE (2017), 10071, 30-40.
110. Herrmannsdörfer F, Flottmann B, Nanguneri S, Venkataramani V, Horstmann H, Kuner T, Heilemann M, 3D dSTORM imaging of fixed brain tissue. Methods Mol Biol. (2017), 1538:169-184.
2016
109. Diekmann, R.; Wolfson, D. L.; Spahn, C.; Heilemann, M.; Schüttpelz, M. & Huser, T. (2016) Nanoscopy of bacterial cells immobilized by holographic optical tweezers.Nat Commun. 7:13711. doi:10.1038/ncomms13711.
108. Spahn, C.; Herrmannsdörfer, F.; Kuner, T. & Heilemann, M. (2016). Cluster analysis through temporal subsampling. Nat Methods 13(12):963–964.
107. Hummer, G.; Fricke, F. & Heilemann, M. (2016) Model-independent counting of molecules in single-molecule localization microscopy. Mol Biol Cell. 27(22):3637-3644.
106. Zeuner, M.-T.; Krüger, C. L.; Volk, K.; Bieback, K.; Cottrell, G. S.; Heilemann, M. & Widera, D. (2016). Ligand-Biased Regulation of Inflammatory Balance is an Essential Feature of TLR4 in Glioma Cells. Biochim Biophys Acta. 1863(12):3084-3095.
105. Fricke, F.; Beaudouin, J.; Malkusch, S.; Eils, R. & Heilemann, M. (2016). Quantitative single-molecule localization microscopy (qSMLM) of membrane proteins based on kinetic analysis of fluorophore blinking cycles. In: Erfle H. (eds) Super-Resolution Microscopy. Methods in Molecular Biology, vol 1663. Humana Press, New York, NY.
104. Malkusch, S. and Heilemann, M. (2016). Extracting quantitative information from single Molecule super-resolution imaging data with LAMA – LocAlization Microscopy Analyzer. Sci. Rep. 6, 34486;
103. Hanne, J.; Zila, V.; Heilemann, M.; Müller, B. & Kräusslich, H.-G. (2016). Super-resolved insights into human immunodeficiency virus biology. FEBS Letters, 590(13), 1858-76.
102. Widera, D.; Klenke, C.; Nair, D.; Heidbreder, M.; Sibarita, J. B.; Choquet, D.; Kaltschmidt, B.; Heilemann, M. & Kaltschmidt, C. (2016). Single-molecular localization microscopy reveals an influence of glutamate on the lateral dynamics of NF-kB in neurites of living hippocampal neurons. Neurophotonics, 3(4):041804.
101. Venkataramani, V.; Herrmannsdörfer, F.; Heilemann, M. & Kuner, T. (2016). SuReSim - Simulating localization microscopy experiments from ground truth models. Nat Methods 13, 319-321.
100. Zessin, P.; Sporbert, A. & Heilemann, M. (2016). PCNA shows two modes of mobility with a constant ratio throughout S-phase in replicating mammalian cells. Scientific Reports 6, 18779.
99. Kollmannsperger, A.; Sharei, A.; Raulf, A.; Heilemann, M.; Langer, R.; Jensen, K. F.; Wieneke, R. & Tampé, R. (2016). High-content live-cell protein labeling with nanometer precision by cell squeezing. Nature Communication 7:10372.
2015
98. Friedrich, F.; Klehs, K.; Fichte, M. A. H.; Junek, S.; Heilemann, M. & Heckel, A. (2015). A two-photon activatable amino acid linker for the induction of fluorescence. Chem Comm,
97. Fricke, F.; Beaudouin, J.; Eils, R. & Heilemann, M. (2015). One, two, three: subunit counting with SMLM. Scientific Reports 5, 14072.
96. Devraj, K.; Poznanovic, S.; Spahn, C.; Schwall, G.; Harter, P.; Mittelbronn, M.; Antoniello, K.; Paganetti, P.; Muhs, A.; Heilemann, M.; Hawkins, R. A.; Schrattenholz, A. & Liebner, S. (2015). BACE-1 is expressed in the blood-brain barrier endothelium and is upregulated in a murine model of Alzheimer's disease. Journal of Cerebral Blood Flow & Metabolism, 36(7), 1281-94.
95. Finan, K.; Raulf, A. & Heilemann, M. (2015). A set of homo-oligomeric standards allows accurate protein counting. Angewandte Chemie 54(41), 12049-12052.
94. Foo, Y. H.; Spahn, C.; Zhang, H.; Heilemann, M. & Kenney, L. J. (2015). Single cell super-resolution imaging of E. coli OmpR during environmental stress. Integr. Biol., 7, 1297-1308.
93. Volz, Y.; Koschut, D.; Matzke, A.; Dietz, M. S.; Karathanasis, C.; Richert, L.; Wagner, M. G.; Mely, Y.; Heilemann, M.; Niemann, H. H. & Orian-Rousseau, V. (2015). Direct binding of hepatocyte growth factor and vascular endothelial growth factor to CD44v6. Bioscience Reports Jun 29, 2015,
92. Wieneke, R.; Raulf, A.; Kollmannsperger, A.; Heilemann, M. & Tampé, R. (2015). SLAP: Small Labeling Pair for Single-Molecule Super-Resolution Imaging. Angewandte Chemie 127(35), 10354-10357.
91. Seybold, C.; Elserafy, M.; Rüthnick, D.; Ozboyaci, M.; Neuner, A.; Flottmann, B.; Heilemann, M.; Wade, R. C. & Schiebel, E. (2015). Kar1 binding to Sfi1 C-terminal regions anchors the SPB bridge to the nuclear envelope. JCB vol. 209 no. 6, 843-861.
90. Palayret, M.; Armes, H.; Basu, S.; Watson, A. T.; Herbert, A.; Lando, D.; Etheridge, T. J.; Endesfelder, U.; Heilemann, M.; Laue, E.; Carr, A. M.; Klenerman, D. & Lee, S. F. (2015). Virtual light-sheet imaging enables optical sectioning in super-resolution microcsopy. PLoS ONE 10(4): e0125438.
89. Fricke, F.; Dietz, M. S. Heilemann, M. (2015). Single-molecule methods to study membrane receptor oligomerization. ChemPhysChem 2015, 16, 713 – 721.
88. Spahn, C.; Cella-Zannacchi, F.; Endesfelder, U. & Heilemann, M. (2015). Correlative super-resolution imaging of RNA polymerase distribution and dynamics, bacterial membrane and chromosomal structure in E. coli. Methods and Applications inFluorescence. Methods Appl. Fluoresc. 3 014005.
2014
87. Nandi, C.K., Barth, H.-D., Brutschy, B. (2014). A new liquid droplet laser desorption source combined with supersonic jet expansion: Application to phenol and its water clusters. Z. Phys. Chem. 228, 449-457.
86. Endesfelder, U. (2014) Advances in Correlative Single-Molecule Localization Microscopy and Electron Microscopy. NanoBioImaging 1, 29–37.
85. Raulf, A., Spahn, C., Zessin, P. J. M., Finan K., Bernhardt S., Heckel A. & Heilemann, M. (2014). Click chemistry facilitates direct labeling and super-resolution imaging of nucleic acids and proteins. RSC Adv., 2014,4, 30462-30466.
84. Perkovic, M.; Kunz, M.; Endesfelder, U.; Bunse, S.; Wigge, C.; Yu, Z.; Hodirnau, V.; Scheffer, M.P.; Seybert, A.; Malkusch, S.; Schuman, E.M.; Heilemann, M. & Frangakis, A.M. (2014). Correlative Light- and Electron Microscopy with chemical tags. J Struct Biol, 186(2), 205-13.
83. Endesfelder, U. & Heilemann, M. (2014). Art and artifacts in single-molecule localization microscopy: beyond attractive images. Nature Methods 11, 235-238.
82. Fricke, F.; Malkusch, S.; Wangorsch, G.; Greiner, J. F.; Kaltschmidt, B.; Kaltschmidt, C.; Widera, D.; Dandekar, T. & Heilemann, M. (2014). Quantitative single-molecule localization microscopy combined with rule-based modeling reveals ligand-induced TNF-R1 reorganization towards higher order oligomers. Histochemistry and Cell Biology, 142(1), 91-101.
81. Diez, L. T.; Bönsch, C.; Malkusch, S.; Truan, Z.; Munteanu, M.; Heilemann, M.; Hartley, O.; Endesfelder, U. & Fürstenberg, A. (2014). Coordinate-based co-localization mediated analysis of arrestin clustering upon stimulation of the C-C chemokine receptor 5 with RANTES analogues. Histochemistry and Cell Biology, 142(1), 69-77.
80. Gunkel, M.; Flottmann, B.; Heilemann, M.; Reymann, J. & Erfle, H. (2014). Integrated and correlative high-throughput and super-resolution microsgopy. Histochemistry and Cell Biology, 141(6), 597-603.
79. Endesfelder, U.; Malkusch, S.; Fricke, F. & Heilemann, M. (2014). A simple method to estimate the average localization precision of a single-molecule localization microscopy experiment. Histochemistry and Cell Biology, 141(6), 629-38.
78. Nanguneri, S.; Flottmann, B.; Herrmannsdörfer, F.; Kuner, T. & Heilemann, M. (2014). Single-molecule super-resolution imaging by tryptophan-quenching-induced photoswitching of phalloidin-fluorophore-conjugates. J Microsc Res Tech, 77(7), 510-6.
77. Spahn, C.; Endesfelder, U. & Heilemann, M. (2014). Super-resolution imaging of Escherichia coli chromosomes reveals asymmetric replication and segregation. J. Struct Biol. 185, 243-249.
76. Klehs, K.; Spahn, C.; Endesfelder, U.; Lee, S. L.; Fürstenberg, A. & Heilemann, M. (2013). Increasing the brightness of carbocyanine fluorophores. ChemPhysChem 15, 637-641.
75. Dietz, M.; Fricke, F.; Krüger, C.; Niemann, H. H. & Heilemann, M. (2013). Receptor-ligand interactions: binding affinities studied with single-molecule and super-resolution microscopy on intact cells. ChemPhysChem 15, 671-676.
2013
74. Sroka, R.; Pongratz, T.; Siegrist, K.; Burgmeier, C.; Barth, H.D.; Schmedt, C.G. (2013). Endovenous laser application strategies to improve endoluminal energy application. Phlebologie 42(3), 121-129
73. Flottmann, B.; Gunkel, M.; Lisaukas, T.; Heilemann, M. ; Starkuviene, V.; Reymann, J. & Erfle, H. (2013). Correlative light microscopy for high-content screening. BioTechniques 2013, 55(5), 243–252
72. Truan, Z.; Börsch, C.; Malkusch, S.; Endesfelder, U.; Munteanu, M.; Hartley, O.; Heilemann, M. & A. Fürstenberg (2013). Quantitative morphological analysis of arrestin2 clustering upon G protein-coupled receptor stimulation by super-resolution microscopy. J Struct Biol. 2013, 184(2), 329-34.
71. Zessin, P.; Krüger, C.; Malkusch, S.; Endesfelder, U. & Heilemann, M. (2013). A non-linear drift-correction and channel-alignment method for localization microscopy techniques using uniform 3D distributions of fiducial markers. Optical Nanoscopy 2013, 2-4
70. Fürstenberg, A. & Heilemann, M. (2013) Single-molecule localization microscopy – near-molecular spatial resolution in light microscopy with photoswitchable fluorophores. PhysChemChemPhys, 15(36), 14919-30.
69. Müller, B. & Heilemann, M.(2013) Shedding new light on viruses: super-resolution microscopy for studying human immunodeficiency virus. Trends Microbiol. 2013, 21(10), 522-33.
68. Endesfelder, U.; Finan, K.; Holden, S. J.; Cook, P. R.; Kapanidis, A. K. & Heilemann, M. (2013) Nanoscale organization of RNA polymerase in E. coli. Biophys J. 105(1), 172-81.
67. Dietz, M.; Haße, D.; Ferraris, D. M.; Göhler, A.; Niemann, H. H. & Heilemann, M. (2013). Single-molecule photobleaching reveals MET receptor dimerization upon ligand binding in intact cells. BMC Biophysics, 6(1), 6.
66. Sporbert, A.; Cseresnyes, Z.; Heidbreder, M.; Domaing, P.; Hauser, S.; Kaltschmidt, B.; Kaltschmidt, C.; Heilemann, M. & Widera, D. (2013) Simple method for sub-diffraction resolution imaging of cellular structures on standard confocal microscopes by three-photon absorption of quantum dots. PLoS One, 8(5), e64023.
65. Kechkar, A.; Nair, D.; Heilemann, M.; Choquet, D. & Sibarita, J. B. (2013) Real-time analysis and visualization for single-molecule based super-resolution microscopy. PLoS One, 8(4), e62918.
64. Muranyi, W.; Malkusch, S.; Müller, B.; Heilemann, M.& Kräusslich, H.-G. (2013) Super-resolution Microscopy Reveals Specific Recruitment of HIV-1 Envelope Proteins to Viral Assembly Sites dependent on the Envelope C-Terminal Tail. PLoS Pathogens 9(2), e1003198.
63. Finan, K.; Flottmann, B. & Heilemann, M. (2013) Photoswitchable fluorophores for single-molecule loclization microscopy. Methods in Molecular Biology, 950, 131-151.
62. Malkusch, S.; Muranyi, W.; Müller, B.; Kräusslich, H.-G. & Heilemann, M. (2012) Single-molecule, coordinate-based analysis of the morphology of HIV assembly sites with near-molecular spatial resolution. Histochemistry and Cell Biology, 139(1), 173-179
2012
61. Sibarita, J. B. & Heilemann, M (2012) Targeting, resolving and quantifying cellular structures by single-molecule localization microscopy. EMBO Reports, 13(12), 1043-1045
60. Dutta, S.; Flottmann, B.; Heilemann, M. & Mokhir, A. (2012) Hybridization and reaction-based, fluorogenic nucleic acid probes. Chemical Communications, 48(77), 9664-6.
59. Neugart, F.; Widera, D.; Kaltschmidt, B.; Kaltschmidt, C. & Heilemann, M. (2012) TNF receptor membrane dynamics studied with fluorescence microscopy and spectroscopy. In: Fluorescent Methods to Study Biological Membranes. Springer Series on Fluorescence, Springer: 439–457.
58. Heidbreder, M.; Zander, C.; Malkusch, S.; Widera, D.; Kaltschmidt, B.; Kaltschmidt, C.; Nair, D.; Choquet, D.; Sibarita, J.-B. & Heilemann, M. (2012) TNFalpha influences the lateral dynamics of TNF receptor I in living cells. BBA – Molecular Cell Research, 1823(10), 1984-9.
57. Lando, D.; Endesfelder, U.; Berger, H.; Dunne, P. D.; McColl, J.; Klenerman, D.; Carr, A. M.; Sauer, M.; Allshire, R.; Heilemann, M. & Laue, E. D. (2012) Quantitative single molecule microscopy reveals that CENP-Acnp1 deposition occurs during G2 in fission yeast. Open Biology, 2, 120078.
56. Bar-on, D.; Wolter, S.; van de Linde, S.; Heilemann, M.; Nachliel, E.; Gutman, M.; Sauer, M. & Ashery, U. (2012) Super-resolution imaging reveals the internal architecture of nano-sized syntaxin clusters. Journal of Biological Chemistry, 287, 27158-67.
55. Nangunieri, S.; Flottmann, B.; Horstmann, H.; Heilemann, M. & Kuner, T. (2012) Three-dimensional, tomographic super-resolution fluorescence imaging of serially sectioned thick samples. Plos ONE, 7, e38098.
54. Brodehl, A.; Hedde, P. N.; Dieding, M.; Fatima, A.; Walhorn, V.; Gayda, S.; Saric, T.; Klauke, B.; Gummert, J.; Anselmetti, D.; Heilemann, M.; Nienhaus, G. U. & Milting, H. (2012) Molecular insights into filament assembly defects of ARVC-related desmin mutations. Journal of Biological Chemistry, 287, 16047-16057.
53. Lampe, A.; Haucke, V.; Heilemann, M. & Schmoranzer, J. (2012) Multi-color direct STORM with red emitting carbocyanines. Biology of the Cell, 104, 229-237.
52. van de Linde, S.; Heilemann, M. & Sauer, M. (2012) Live-cell super-resolution imaging with synthetic fluorophors. Annual Reviews of Physical Chemistry, 63, 519-540.
51. Löschberger, A.; van de Linde, S.; Dabauvalle, M.-C.; Rieger, B.; Heilemann, M.; Krohne, G. & Sauer, M. (2012) Super-resolution imaging reveals eightfold symmetry of gp210 proteins around the nuclear pore complex and resolves the central channel with nanometer resolution. J Cell Science, 125, 570-575.
50. Heilemann, M. (2012) Elucidating Cellular Structures – Superresolution Microscopy. Comprehensive Biophysics, Elsevier.
49. Zessin, P. J. M.; Finan, K. & Heilemann, M. (2012) Super-resolution fluorescence imaging of chromosomal DNA using click chemistry. Journal of Structural Biology, 177, 344-348.
48. Dertinger, T..; Colyer, R.; Vogel, R.; Heilemann, M.; Sauer, M.; Enderlein, J. & Weiss, S.. (2012) Super-resolution optical fluctuation imaging (SOFI). Advances in Experimental Medicine and Biology, 733, 17-21.
47. Malkusch, S.; Endesfelder, U.; Mondry, J.; Gelléri, Martón; Verveer, P. J. & Heilemann, M. (2012) Coordinate-based colocalization analysis of single-molecule localization microscopy data. Histochem Cell Biology, 137, 1-10.
2011
46. Eckhardt, M.; Anders, M.; Muranyi, W.; Heilemann, M.; Krijnse-Locker, J. & Müller, B. (2011) A SNAP-Tagged Derivative of HIV-1 – a Versatile Tool to Study Virus-Cell Interactions. PlosONE, 6(7), e22007.
45. van de Linde, S.; Löschberger, A.; Klein, T.; Heidbreder, M.; Wolter, S.; Heilemann, M. & Sauer, M. (2011) Direct stochastic optical reconstruction microscopy with standard fluorescent probes. Nature Protocols, 6(7), 991-1009.
44. Widera, D.; Heimann, P.; Zander, C.; Imielski, Y.; Heidbreder, M.; Heilemann, M.; Kaltschmidt, C. & Kaltschmidt, B. (2011) Myalinating Schwann Cells can be reprogrammed to multipotency by culture. Stem Cells and Development, 20(12), 2053-2064.
43. Endesfelder, U.; Malkusch, S.; Flottmann, B.; Mondry, J.; Liguzinski, P.; Verveer, P. J. & Heilemann, M. (2011) Chemically induced photoswitching of fluorescent probes – a general concept for super-resolution imaging. Molecules, 16, 3106-3118.
42. Wolter, S.; Endesfelder, U.; van de Linde, S.; Heilemann, M. & Sauer, M. (2011) Measuring localization performance of super-resolution algorithms on very active samples. Optics Express 19(8), 7020-7033.
41. van de Linde, S.; Krstic, I.; Prisner, T.; Doose, S.; Heilemann, M. & Sauer, M. (2011) Photoinduced formation of stable dye radicals. Photochemical & Photobiological Sciences, 10, 499-506.
2010
40. Kottke, T.; van de Linde, S.; Sauer, M.; Kakorin, S. & Heilemann, M. (2010) Identification of the Product of Photoswitching of an Oxazine Fluorophore Using Fourier Transform Infrared Difference Spectroscopy. Physical Chemistry Letters, 1, 3156-3159.
39. Dertinger, T.; Heilemann, M. ; Vogel, R.; Sauer, M. & Weiss, S. (2010) Superresolution Optical Fluctuation Imaging with Organic Dyes. Angewandte Chemie, 49, 9441-9443.
38. Zheng, Z.; Nottbohm, C. T.; Turchanin, A.; Muzik, H.; Beyer, A.; Heilemann, M.; Sauer, M.; Gölzhäuser, M. (2010) Janus nanomembranes: bilaterally functionalized freestanding 1 nm thick carbon membranes. Angewandte Chemie, 49, 8493-8497.
37. Wombacher, R.; Heidbreder, M.; van de Linde, S.; Sheetz, M. P.; Heilemann, M. ; Cornish, V. W. & Sauer, M. (2010) Live-cell super-resolution imaging of core histones with trimethoprim conjugates. Nature Methods, 7, 717-719.
36. Uphoff, S.; Holden, S.; Le Reste, L.; van de Linde, S.; Heilemann, M. & Kapanidis, A. N. (2010) Monitoring multiple distances within a single molecule using switchable FRET. Nature Methods, 7, 831-836.
35. Heidbreder, M.; Endesfelder, U.; van de Linde, S.; Hennig, S.; Widera, D.; Kaltschmidt, B.; Kaltschmidt C. & Heilemann, M. (2010) Subdiffraction Fluorescence Microscopy of Biomolecular Structure and Distributions with Quantum Dot Triexciton Imaging (QDTI). Biochimica et Biophysica Acta, 1803, 1224-1229.
34. Hohlbein, J.; Gryte, K.; Heilemann, M. & Kapanidis, A. N. (2010) Surfing on a new wave of single-molecule fluorescence methods. Physics and Biology, 7, 031001.
33. Heilemann, M. (2010) Fluorescence microscopy beyond the diffraction limit. Journal of Biotechnology, 149, 243-251.
32. van de Linde, S.; Wolter, S.; Heilemann, M. & Sauer, M. (2010) The effect of photoswitching kinetics and labeling densities on super-resolution fluorescence imaging. Journal of Biotechnology, 149, 260-266.
31. Nottbohm, C. T.; Sopher, R.; Heilemann, M.; Sauer, M. & Golzhäuser A. (2010) Fluorescently labeled 1 nm thin carbon nanomembranes. Journal of Biotechnology, 149, 267-271.
30. Endesfelder, U.; van de Linde, S.; Wolter, S.; Sauer, M & Heilemann, M. (2010) Subdiffraction-Resolution Fluorescence Microscopy of Myosin-Actin Motility. ChemPhysChem, 11, 836-840.
29. Seefeldt, B; Kasper, R.; Beining, M.; Mattay, J.; Arden-Jacob, J.; Kemnitzer, N.; Drexhage, K. H.; Heilemann, M. & Sauer, M. (2010) Spiropyrans as molecular optical switches. Photochemical & Photobiological Sciences, 9, 213-220.
28. Lymperopoulos, K.; Crawford, R.; Torella, J. P.; Heilemann, M.; Hwang, L. C.; Holden, S. J. and Kapanidis, A. N. (2010) Single-molecule DNA biosensors for protein and ligand detection. Angewandte Chemie, 49, 1316-1320.
27. Wolter, S.; Schüttpelz, M.; Tscherepanow, M.; van de Linde, S.; Heilemann, M. & Sauer, M. (2010) Real-time computation for subdiffraction-resolution fluorescence images. Journal of Microscopy, 237(1), 12-22.
2009
26. Heilemann, M. ; van de Linde, S.; Mukherjee, A. & Sauer, M. (2009) Super-resolution imaging with small organic fluorophores. Angewandte Chemie, 48, 6903-8.
25. Heilemann, M. & Sauer, M. (2009) Superhochauflösung: Mikroskopie unterhalb des Beugungslimits mit konventionellen Fluoreszenzfarbstoffen. Labor & more, 04-09, 32-34.
24. Hennig, S.; van de Linde, S.; Heilemann, M. & Sauer, M. (2009) Quantum dot triexciton imaging with three-dimensional subdiffraction resolution. Nanoletters, 9, 2466-70.
(highlighted in Nature Materials, 8, 536 (2009))
23. Heilemann, M. (2009) Light at the End of the Tunnel. Angewandte Chemie, 48, 3908-10.
22. Heilemann, M.; Lymperopoulos, K.; Hwang, L. C. & Kapanidis, A. (2009) Single-Molecule FRET-Analysis of protein-DNA complexes. Methods in Molecular Biology, 543, 503-521.
21. van de Linde, S.; Endesfelder, U.; Mukherjee, A.; Schüttpelz, M.; Wiebusch, G.; Wolter, S.; Heilemann, M. & Sauer, M. (2009) Multicolor Photoswitching Microscopy for Subdiffraction Resolution Fluorescence Imaging. Photochemical and Photobiological Sciences, 8, 465-469.
20. Heilemann, M. ; Dedecker, P.; Hofkens, J. & Sauer, M. (2009) Photoswitches: Key Molecules for Subdiffraction-Resolution Fluorescence Imaging and Molecular Quantification. Laser and Photonics Reviews, 3, 180-202.
2008
19. van de Linde, S.; Kasper, R.; Heilemann, M. & Sauer, M. (2008) Photoswitching Microscopy with Standard Fluorophores. Applied Phys. B, 93, 725-731.
18. van de Linde, S.; Sauer, M. & Heilemann, M. (2008) Subdiffraction-Resolution Fluorescence Imaging of Proteins in the Mitochondrial Inner Membrane with Photoswitchable Fluorophores. Journal of Structural Biology, 164, 250-254.
17. Heilemann, M. ; van de Linde, S.; Schüttpelz, M.; Kasper, R.; Seefeldt, B.; Mukherjee, A.; Tinnefeld, P. & Sauer, M. (2008) Subdiffraction-Resolution Fluorescence Imaging with Conventional Fluorescent Probes. Angew. Chemie, 47, 6172-6176.
16. Goodman, R. P.; Heilemann, M.; Doose, S.; Kapanidis, A. N. & Turberfield, A. J. (2008) Reconfigurable, Braced, Three-Dimensional DNA Nanostructures. Nature Nanotechnology 3, 93-96.
15. Seefeldt, B.; Kasper, R.; Seidel, T.; Tinnefeld, P.; Dietz, K.-J.; Heilemann, M. & Sauer, M. (2008) Fluorescent Proteins for Single-Molecule Fluorescence Applications. Journal of Biophotonics 1, 74-82.
14. Vogelsang, J.; Kasper, R.; Steinhauer, C.; Person, B.; Heilemann, M.; Sauer, M. & Tinnefeld, P. (2008). A reducing and oxidizing system minimizes photobleaching and blinking of fluorescent dyes. Angew. Chemie 47, 5465-5469.
2007
13. Roth, C. M., Heinlein, P. I., Heilemann, M. & Herten, D. P. (2007). Imaging diffusion in living cells using time-correlated single-photon counting. Anal Chem 79, 7340-5.
12. Doose, S., Heilemann, M., Michalet, X., Weiss, S. & Kapanidis, A. N. (2007). Periodic acceptor excitation spectroscopy of single molecules. Eur Biophys J 36, 669-74.
11. Clifford, J. N., Bell, T. D., Tinnefeld, P., Heilemann, M., Melnikov, S. M., Hotta, J., Sliwa, M., Dedecker, P., Sauer, M., Hofkens, J. & Yeow, E. K. (2007). Fluorescence of single molecules in polymer films: sensitivity of blinking to local environment. J Phys Chem B 111, 6987-91.
2006
10. Sanchez-Mosteiro, G., van Dijk, E. M., Hernando, J., Heilemann, M., Tinnefeld, P., Sauer, M., Koberling, F., Patting, M., Wahl, M., Erdmann, R., van Hulst, N. F. & Garcia-Parajo, M. F. (2006). DNA-based molecular wires: multiple emission pathways of individual constructs. J Phys Chem B 110, 26349-53.
9. Heilemann, M., Kasper, R., Tinnefeld, P. & Sauer, M. (2006). Dissecting and reducing the heterogeneity of excited-state energy transport in DNA-based photonic wires. J Am Chem Soc 128, 16864-75.
2005
8. Tinnefeld, P., Heilemann, M. & Sauer, M. (2005). Design of molecular photonic wires based on multistep electronic excitation transfer. Chemphyschem 6, 217-22.
7. Heinlein, T., Biebricher, A., Schlüter, P., Roth, C. M., Herten, D. P., Wolfrum, J., Heilemann, M., Muller, C., Tinnefeld, P. & Sauer, M. (2005). High-resolution colocalization of single molecules within the resolution gap of far-field microscopy. Chemphyschem 6, 949-55.
6. Heilemann, M., Margeat, E., Kasper, R., Sauer, M. & Tinnefeld, P. (2005). Carbocyanine dyes as efficient reversible single-molecule optical switch. J Am Chem Soc 127, 3801-6.
2004 and before
5. Tinnefeld, P., Buschmann, V., Weston, K. D., Biebricher, A., Herten, D. P., Piestert, O., Heinlein, T., Heilemann, M.& Sauer, M. (2004). How single molecule photophysical studies complement ensemble methods for a better understanding of chromophores and chromophore interactions. Recent Res. Devel. Phys. Chem. 7, 95-125.
4. Herten, D. P., Biebricher, A., Heilemann, M., Heinlein, T., Müller, C., Schlüter, P., Tinnefeld, P., Weston, K. D., Sauer, M. & Wolfrum, J. (2004). Optical single molecule techniques for analytical and biological applications. Recent Res. Devel. Applied Phys. 7, 2-24.
3. Heilemann, M., Tinnefeld, P., Sanchez Mosteiro, G., Garcia Parajo, M., Van Hulst, N. F. & Sauer, M. (2004). Multistep energy transfer in single molecular photonic wires. J Am Chem Soc 126, 6514-5.
(highlighted in Science, 304, 5675 (2004))
2. Devos, I., Womes, M., Heilemann, M., Olivier-Fourcade, J., Jumas, J.-C. & Tirado, J. L. (2004). Lithium insertion mechanism in CoSb3 analysed by 121Sb Moessbauer spectrometry, X-ray absorption spectroscopy and electronic structure calculations. J. Mat. Chem. 14, 1759-67.
1. Heilemann, M., Herten, D. P., Heintzmann, R., Cremer, C., Muller, C., Tinnefeld, P., Weston, K. D., Wolfrum, J. & Sauer, M. (2002). High-resolution colocalization of single dye molecules by fluorescence lifetime imaging microscopy. Anal Chem 74, 3511-7.
